Ask an ABTA Researcher
Introducing Ask an ABTA Researcher. Starting this month, we will be including Q&A's with ABTA-funded researchers. The ABTA receives so many great questions from patients, caregivers and supporters across the country, that we thought it would be great to share the questions we get, and more importantly the answers.
Q: What is the difference between the “genetics” of brain tumors and “hereditary factors” involved in brain tumor risk?
Answer provided by Kyle M. Walsh, PhD, University of California, San Francisco. Dr. Walsh is using epidemiology to understand how the risk for brain tumors can be inherited across generations. Click here to read Dr. Walsh’s full answer.
We would love to hear from you. If you have a question you would like to submit, click here.
Find Out What’s New Near You
New Immune Vaccine Shows Promise
Purposeful manipulation of the immune system may offer a promising way of improving outcomes for patients with glioblastoma (GBM). A recent study of a new vaccine, whose research was partially funded by the ABTA, appeared to improve median survival (the point at which an equal number of people do better as do worse) for those with a recurrent GBM. The vaccine, called HSPPC-96, is a protein that can be extracted from a patient’s own tumor to form a vaccine. The treatment appeared to boost the patient’s own immune response and increase the effectiveness of other therapies. Read more about the results of this phase II clinical trial here.
Understanding Treatment Resistance
One of the challenges of treating malignant tumors is a phenomenon called treatment resistance – the innate ability of tumor cells to grow resistant to a therapy to which they may have originally responded. Understanding how that resistance happens, and what researchers are doing to counter this effect, is the topic of the feature story in the Winter 2013 issue of CURE magazine. One of the approaches targets mitochondria – the energy producing part of a tumor cell and a drug development strategy that a recent ABTA Discovery Grant is helping to support. Read more about these innovative ways of “outsmarting” cancer cells here.
Wednesday, Feb. 12 at 1 p.m. – Causes and Risk Factors of Brain Tumors. Join Jill Barnholtz-Sloan, PhD, associate professor at Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine to hear updates on what we know about some causes and risk factors of brain tumors. Click here to RSVP.
Thursday, Feb. 27 at 2 p.m. – Diagnosis, Management and Treatment of Medulloblastoma. Paul Fisher, MD, MHS, professor of Neurology and Pediatrics, division chief of Neurology at Stanford University and Lucile Salter Packard Children’s Hopital will discuss many discoveries, including new laboratory genomics that are rapidly shaping treatments. Click here to RSVP.
Wednesday, March 19 at 2 p.m. – Managing Survivorship for Adolescents and Young Adults who had Pediatric Brain Tumors. Stewart Goldman, MD, and Jennifer Reichek, MD, MSW, both of Ann & Robert H. Lurie Children’s Hospital of Chicago will discuss the different needs of adolescent and young adult brain tumor survivors, including social skills, dating, education, employment and more. Click here to RSVP.
Thursday, March 27 at 2 p.m. – Metastatic Brain Tumors: A Treatment and Care Update. Join co-presenters Duane Mitchell, MD, PhD and Maryam Rahman, MD, of the Department of Neurosurgery, University of Florida, as they address treatment options of metastatic tumors, quality of life concerns, status of the primary cancer and more. Click here to RSVP.
Join Erin as She Makes Breakthroughs
Each day, 500 people are diagnosed with a brain tumor. One fateful day, Erin D’Addio was one of those 500. Today, Erin is a survivor and she is helping others who face a brain tumor diagnosis by participating in a Breakthrough for Brain Tumors 5K Run & Walk!
Join Erin, and hundreds of others, as we make breakthroughs in brain tumor research and care. Visit www.bt5k.org to sign up for an event near you.
Secure Your Spot for the Chicago Marathon
The Bank of America Chicago Marathon is switching to a lottery-style registration system this year, but we can save a bib for you! Join Team Breakthrough and receive a guaranteed entry to the 2014 Chicago Marathon, plus other exclusive benefits including a comprehensive training program, a personal fundraising webpage, fundraising support, team pasta dinner the night before the race, and much more.